| Chemical Properties | Back Directory | [Boiling point ]
1529.3±65.0 °C(predicted) | [density ]
1.25±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
13.29±0.70(predicted) |
| Hazard Information | Back Directory | [Uses]
DBCO-PEG2-Val-Cit-PAB-MMAE is an ADC linker featuring a DBCO group, a Val-Cit dipeptide, a PAB motif, and an MMAE warhead. The DBCO group is a click chemistry handle which readily reacts with azide groups, while the Val-Cit is a protease-cleavable dipeptide which releases the MMAE warhead into cells via an elimination mechanism. |
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