| Identification | Back Directory | [Name]
3-azabicyclo[3.1.0]hexane | [CAS]
285-59-6 | [Synonyms]
UKRORGSYN-BB BBV-265866
3-azabicyclo[3.1.0]hexane
3-Azabicyclo[3.1.0]hexane (8CI, 9CI, ACI) | [Molecular Formula]
C5H9N | [MDL Number]
MFCD10696889 | [MOL File]
285-59-6.mol | [Molecular Weight]
83.13 |
| Hazard Information | Back Directory | [Uses]
3-Azabicyclo[3.1.0]hexane is a key structural feature found in a wide range of biologically active natural products, drugs, and agrochemicals.
| [Synthesis]
3-azabicyclo[3.1.0]hexane synthesis: 1-Chlorocyclopropyl p-tolyl sulfoxides with an N,N-disubstituted aminomethyl group on the cyclopropane ring were prepared from dichloromethyl p-tolyl sulfoxide, α,β-unsaturated carboxylic acid esters, primary amines, and alkyl halides. Treatment of the sulfoxides with i-PrMgCl generated cyclopropylmagnesium carbenoids, which were inserted into an intramolecular C–H bond adjacent to a nitrogen atom to give 3-azabicyclo[3.1.0]hexane in yields of up to 94%. |
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| Company Name: |
SynAsst Chemical.
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021-60343070 |
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www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
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Struchem Co., Ltd.
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0512-63009836 18994340901 |
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http://www.beidapharma.com |
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SPIRO PHARMA
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www.spiropharma.com.cn |
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parabiochem
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025-83453382-8005 |
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www.parabiochem.cn |
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