| Identification | Back Directory | [Name]
1,2-Ethanediamine, N1-[5-chloro-6-methyl-2-(2-pyridinyl)-4-pyrimidinyl]-N2-[6-(trifluoromethyl)-2-pyridinyl]- | [CAS]
286008-51-3 | [Synonyms]
RDR03871
RDR-03871
RDR 03871
1,2-Ethanediamine, N1-[5-chloro-6-methyl-2-(2-pyridinyl)-4-pyrimidinyl]-N2-[6-(trifluoromethyl)-2-pyridinyl]- | [Molecular Formula]
C18H16ClF3N6 | [MOL File]
286008-51-3.mol | [Molecular Weight]
408.81 |
| Hazard Information | Back Directory | [Description]
RDR03871 is an MDM2 inhibitor. Inactivation of the tumor suppressor p53 and/or overexpression of the oncogene MDM2 frequently occur in human cancers, and are associated with poor prognosis, advanced forms of the disease, and chemoresistance. MDM2, the major negative regulator of p53, induces p53 degradation and inactivates its tumor suppressing activity. |
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