| Chemical Properties | Back Directory | [Boiling point ]
642.937±65.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.405±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
3.872±0.10(predicted) |
| Hazard Information | Back Directory | [Uses]
FABP4/5-IN-4 (compound E1) is a potent inhibitor of FABP4 and FABP5, with the IC50s of 3.78 μM and 5.72 μM, respectively. FABP4/5-IN-4 plays an important role in metabolism disorder like diabetes mellitus[1]. | [References]
[1] Yu-Long He, et al. Development of FABP4/5 inhibitors with potential therapeutic effect on type 2 Diabetes Mellitus. Eur J Med Chem. 2021 Nov 15:224:113720. DOI:10.1016/j.ejmech.2021.113720 |
|
|