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2869954-51-6

2869954-51-6 Structure

2869954-51-6 Structure
IdentificationBack Directory
[Name]

[1,2,4]Triazolo[1,5-a]pyrimidine-4(7H)-acetamide, 2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-[4-[(5-hydroxy-6-methyl-4-pyrimidinyl)carbonyl]-1-piperazinyl]-N-[2-methyl-4-(trifluoromethyl)phenyl]-7-oxo-
[CAS]

2869954-51-6
[Synonyms]

Werner syndrome RecQ helicase-IN-2
[1,2,4]Triazolo[1,5-a]pyrimidine-4(7H)-acetamide, 2-(3,6-dihydro-2H-pyran-4-yl)-5-ethyl-6-[4-[(5-hydroxy-6-methyl-4-pyrimidinyl)carbonyl]-1-piperazinyl]-N-[2-methyl-4-(trifluoromethyl)phenyl]-7-oxo-
[Molecular Formula]

C32H34F3N9O5
[MOL File]

2869954-51-6.mol
[Molecular Weight]

681.66
Chemical PropertiesBack Directory
[density ]

1.51±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

5.87±0.45(Predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Werner syndrome RecQ helicase-IN-2 (example 57) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research[1].
[References]

[1] Triazolo-pyrimidine analogues for treating diseases connected to the inhibiton of werner syndrome recq helicase (wrn). WO2022249060
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