| Identification | Back Directory | [Name]
2-[2-(1-Methylethyl)phenyl]-7-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]imidazo[5,1-f][1,2,4]triazine | [CAS]
2878441-72-4 | [Synonyms]
USP1-IN-4
2-[2-(1-Methylethyl)phenyl]-7-[[4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl]methyl]imidazo[5,1-f][1,2,4]triazine | [Molecular Formula]
C26H23F3N6 | [MOL File]
2878441-72-4.mol | [Molecular Weight]
476.5 |
| Hazard Information | Back Directory | [Uses]
USP1-IN-4 (compound 10) is an effective USP1 inhibitor with an IC50 value of 2.44 nM. USP1-IN-4 has anticancer activity and synergistic activity with various anticancer drugs[1]. | [IC 50]
USP1: 2.44 nM (IC50) | [References]
[1] Cai S, et al. Nitrogen-containing fused heteroaromatic bicyclic compounds as USP1 inhibitors and the use thereof. China,WO 2022/253188 A.2022-8-12. |
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