| Identification | Back Directory | [Name]
4-[3-[(8-Chloro-1-methyl-1H-[1,2,3]triazolo[4,5-c]isoquinolin-5-yl)(2,2-difluoroethyl)amino]-5-fluorophenyl]-2-methyl-3-butyn-2-ol | [CAS]
2886717-70-8 | [Synonyms]
DGKα-IN-8
4-[3-[(8-Chloro-1-methyl-1H-[1,2,3]triazolo[4,5-c]isoquinolin-5-yl)(2,2-difluoroethyl)amino]-5-fluorophenyl]-2-methyl-3-butyn-2-ol |
| Hazard Information | Back Directory | [Uses]
DGKα-IN-8 (Example 51) is a DGKα inhibitor (IC50=22.491 nM; EC50=0.256 nM). DGKα-IN-8 can be used to study cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection[1]. | [References]
[1] Julian A Codelli, et al. Diacylglyercol kinase modulating compounds. Patent WO2022271659A1. |
|
|