2889371-04-2

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2889371-04-2 Structure

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[Name] Estrogen receptor antagonist 7
[CAS] 2889371-04-2
[Synonyms] Estrogen receptor antagonist 7

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[Uses] Estrogen receptor antagonist 7 (compound 13) is a potent estrogen receptors (ER) antagonist. Estrogen receptor antagonist 7 has antiproliferative activity against breast and ovarian cancer cells. Anticancer and anti-uterotrophic activities[1].
[References] [1] Ragab MA, et al. Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity. Bioorg Chem. 2022 Feb;119:105554. DOI:10.1016/j.bioorg.2021.105554

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