2889422-86-8

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2889422-86-8 Structure

Identification	Back Directory
[Name] (R)-Sortilin antagonist 1
[CAS] 2889422-86-8
[Synonyms] (R)-Sortilin antagonist 1
[MOL File] 2889422-86-8.mol
[Molecular Weight] 356.42

Chemical Properties	Back Directory
[Boiling point ] 558.068±45.00 °C(Press: 760.00 Torr)(predicted)
[density ] 1.172±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[form ] Solid
[pka] 3.334±0.24(predicted)
[color ] White to off-white

Hazard Information	Back Directory
[Uses] (R)-Sortilin antagonist 1 is a sortilin antagonist that blocks the sortilin mediated apoptosis pathway by interfering with the binding of sortilin to its ligand pro-neurotrophin. (R)-Sortilin antagonist 1 can be used in the study of hearing loss[1].
[References] [1] KJ?LBY Mads Fuglsang, et al. A sortilin antagonist for use in the prevention or treatment of hearing loss.WO2022074119A1.2021-10-07

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