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[D-Leu-4]-OB3 inhibits expressions of pro-inflammatory, proliferative and metastatic genes and?PD-L1?expression. [D-Leu-4]-OB3 stimulates expression of pro-apoptotic genes[1]. | [References]
[1] Yih Ho,et al. Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells.Food Chem Toxicol.?2019 Nov;133:110808. DOI:10.1016/j.fct.2019.110808 |
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