| Chemical Properties | Back Directory | [Boiling point ]
516.055±50.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.409±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
10.788±0.70(predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
BAY-5516 is a inverse-agonist o PPARG, with the IC50 value of 6.1±3.6 nM that has anti-tumor effect[1]. | [References]
[1] Douglas L Orsi, et al. Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. Bioorg Med Chem. 2023 Jan 15:78:117130. DOI:10.1016/j.bmc.2022.117130 |
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Biorbyt Ltd.
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+44 (0)1223 859 353 |
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http://www.biorbyt.com |
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