| Identification | Back Directory | [Name]
1-Propanone, 1-(3-chloro-4-hydroxyphenyl)- | [CAS]
2892-27-5 | [Synonyms]
3-Chloro-4-hydroxypropiophenone
1-Propanone, 1-(3-chloro-4-hydroxyphenyl)-
3-oxo-1-(trifluoromethyl)cyclobutane-1-carbonitril
e | [Molecular Formula]
C9H9ClO2 | [MDL Number]
MFCD00218581 | [MOL File]
2892-27-5.mol | [Molecular Weight]
184.62 |
| Hazard Information | Back Directory | [Preparation]
Preparation by Fries rearrangement of o-chlorophenyl propio nate with aluminium chloride, at 165° for 1 h (98%) or at 110° for 2 h (63%)
Preparation by demethylation of 3-chloro-4-methoxy-propiophenone (m.p. 88°) (m.p. 89–90°) with refluxing pyridinium chloride for 15 min (75%)
Preparation by diazotization of 3-amino-4-hydroxypropiophenone, followed by decomposition of the diazonium salt obtained (52%)
Preparation by chlorination of p-hydroxypropiophenone with chlorine in cooled acetic acid (57%). |
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