| Identification | Back Directory | [Name]
8-BENZYL-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE | [CAS]
28936-94-9 | [Synonyms]
8-BENZYL-1,3,8-TRIAZASPIRO[4.5]DECANE-2,4-DIONE
8-(benzyl)-1,3,8-triazaspiro[4.5]decane-2,4-quinone
8-(Phenylmethyl)-1,3,8-triazaspiro(4.5)decane-2,4-dione
8-(phenylmethyl)-1,3,8-triazaspiro[4.5]decane-2,4-dione
1,3,8-Triazaspiro(4.5)decane-2,4-dione, 8-(phenylmethyl)- | [EINECS(EC#)]
604-604-1 | [Molecular Formula]
C14H17N3O2 | [MDL Number]
MFCD00793797 | [MOL File]
28936-94-9.mol | [Molecular Weight]
259.3 |
| Chemical Properties | Back Directory | [Melting point ]
259-261 °C | [density ]
1.29±0.1 g/cm3(Predicted) | [refractive index ]
1.628 | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
10.07±0.20(Predicted) | [Appearance]
White to off-white Solid | [InChI]
InChI=1S/C14H17N3O2/c18-12-14(16-13(19)15-12)6-8-17(9-7-14)10-11-4-2-1-3-5-11/h1-5H,6-10H2,(H2,15,16,18,19) | [InChIKey]
ISFXLJGTXHSNDU-UHFFFAOYSA-N | [SMILES]
N1C2(CCN(CC3=CC=CC=C3)CC2)C(=O)NC1=O |
| Hazard Information | Back Directory | [Description]
8-benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione is a pharmaceutical intermediate compound that can be used to prepare biologically active compounds. Studies have shown that 1,3, 8-triazo [4.5] decane-2, 4-dione is a novel chemical type of agonist with DOR selectivity. δ -opioid receptors (DOR) are potential targets for the treatment of neurological and mental disorders. These agonists are similar to 1,3, 8-triazo [4.5] decane-4-one analogues and have been reported to be weakly selective NOR agonists with moderate binding affinity for DOR, MOR and KOR. | [Uses]
8-Benzyl-1,3,8-triazaspiro[4.5]decane-2,4-dione is a useful research reagent used in the synthesis of spirohydantoins from basic heterocyclic ketones. | [Toxicology]
mouse: LD > 800 mg/kg (oral) |
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