| Identification | Back Directory | [Name]
Sporidesmolide I | [CAS]
2900-38-1 | [Synonyms]
Sporidesmolide I
N-Methylcyclo(L-Leu-L-Hmb-D-Val-D-Leu-L-Hmb-L-Val-)
Cyclo(L-Hmb-D-Val-D-Leu-L-Hmb-L-Val-N-methyl-L-Leu-)
Cyclo[(2S)-2-hydroxy-3-methylbutanoyl-D-valyl-D-leucyl-(2S)-2-hydroxy-3-methylbutanoyl-L-valyl-N-methyl-L-leucyl] | [Molecular Formula]
C33H58N4O8 | [MOL File]
2900-38-1.mol | [Molecular Weight]
638.84 |
| Hazard Information | Back Directory | [Description]
Sporidesmolide is a depsipeptide originally isolated from S. bakeri that has no activity against a variety of bacteria and fungi. | [Uses]
Sporidesmolide I is the most polar of N-methyl analogues belonging the hexadepsipeptide sporidesmolide complex. Biosynthesis of sporidesmolide I involves the use of D- and L- amino acids utilising two leucine and four valine sub-units, where two of the valines are converted to the corresponding valic acid. The biological activity of sporidesmolide I has not been extensively investigated. | [References]
[1] RUSSELL D W. Sporidesmolide I, a metabolic product of Sporidesmium bakeri Syd.[J]. Biochimica et biophysica acta, 1960, 45: Pages 411-412. DOI: 10.1016/0006-3002(60)91477-3
[2] M M SHEMYARKIN. THE STRUCTURE-ANTIMICROBIAL RELATION OF DEPSIPEPTIDES.[J]. Experientia, 1963, 19: 566-568. DOI: 10.1007/bf02150990 |
|
| Company Name: |
Lynnchem
|
| Telephone: |
86-(0)29-85992781 17792393971 |
| Website: |
http://www.lynnchem.com/ |
|