| Identification | Back Directory | [Name]
2-NITRO-1-PROPANOL | [CAS]
2902-96-7 | [Synonyms]
Ba 51-084789
2-Nitropropanol
EINECS 220-797-0
2-NITROPROPANOL-1
2-Nitro-1-propano
2-NITRO-1-PROPANOL
2-nitropropan-1-ol
1-Propanol, 2-nitro-
2-Nitro-1-propanol >=97%
2-Nitro-1-propanol >=95%
1-Propanol, 2-nitro- (8CI)(9CI) | [EINECS(EC#)]
220-797-0 | [Molecular Formula]
C3H7NO3 | [MDL Number]
MFCD00007398 | [MOL File]
2902-96-7.mol | [Molecular Weight]
105.09 |
| Chemical Properties | Back Directory | [Melting point ]
-20°C (estimate) | [Boiling point ]
72-74 °C1 mm Hg(lit.)
| [density ]
1.185 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.439(lit.)
| [Fp ]
212 °F
| [storage temp. ]
2-8°C
| [form ]
liquid (clear)
| [pka]
7.36±0.13(Predicted) | [color ]
clear green-yellow
| [Water Solubility ]
Slightly soluble in water. | [BRN ]
1748592 | [InChI]
1S/C3H7NO3/c1-3(2-5)4(6)7/h3,5H,2H2,1H3 | [InChIKey]
PCNWBUOSTLGPMI-UHFFFAOYSA-N | [SMILES]
CC(CO)[N+]([O-])=O |
| Hazard Information | Back Directory | [Uses]
2-Nitro-1-propanol is used in an improved synthesis of 2,2,2-trinitroethyl ethers.
| [Definition]
ChEBI: 2-nitro-1-propanol is a C-nitro compound. | [General Description]
2-Nitro-1-propanol inhibits methane production during in vitro ruminal fermentation. It is a useful antimicrobial supplement which reduces carriage of certain food-borne pathogens in animals. | [Synthesis]
To a three-necked round-bottomed flask equipped with a stirring magnet, condenser tube, nitrogen inlet and outlet, and constant-pressure dropping funnel, nitroethane (10 g, 0.13 mol) and triethylamine (0.3 g, 10 mol%) were added sequentially. The resulting light yellow solution was stirred for 10 min and then 37% aqueous formaldehyde solution (21.6 g, 0.27 mol) was added slowly and dropwise over a period of 1 hr. The reaction mixture was stirred continuously at room temperature for 24 h, during which the progress of the reaction was monitored periodically by gas chromatography (GC) to confirm complete conversion of the feedstock. The reaction was terminated after 24 hours and the volatile components were removed using a rotary evaporator. A yellow solution was obtained, which was analyzed by GC to confirm the presence of two target products (2-nitro-1-propanol and 2-nitro-2-methyl-1,3-propanediol). The mixture could be used directly in the subsequent reaction without further purification. | [References]
[1] Patent: EP2468713, 2012, A1. Location in patent: Page/Page column 3-4 |
|
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Sigma-Aldrich
|
| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
|