| Identification | Back Directory | [Name]
3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)- | [CAS]
290297-25-5 | [Synonyms]
Netupitant N-1
Netupitant ITS-3
N-methyl-6-(4-methylpiperazin-1-yl)-4-(o-tolyl)pyridin-3-amine
methyl-[6-(4-methyl-piperazin-1-yl)-4-o-tolyl-pyridin-3-yl]-amine
N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine
N-methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-amine
N-Methyl-4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)-3-aminopyridine
3-PYRIDINAMINE, N-METHYL-4-(2-METHYLPHENYL)-6-(4-METHYL-1-PIPERAZINYL)-
N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine acid
N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine Oxalic acid | [EINECS(EC#)]
1592732-453-0 | [Molecular Formula]
C18H24N4 | [MDL Number]
MFCD11113420 | [MOL File]
290297-25-5.mol | [Molecular Weight]
296.41 |
| Chemical Properties | Back Directory | [Boiling point ]
478.2±45.0 °C(Predicted) | [density ]
1?+-.0.06 g/cm3(Predicted) | [pka]
9.73±0.38(Predicted) | [InChI]
InChI=1S/C18H24N4/c1-14-6-4-5-7-15(14)16-12-18(20-13-17(16)19-2)22-10-8-21(3)9-11-22/h4-7,12-13,19H,8-11H2,1-3H3 | [InChIKey]
LCQDUKXKKBAUIO-UHFFFAOYSA-N | [SMILES]
C1=NC(N2CCN(C)CC2)=CC(C2=CC=CC=C2C)=C1NC |
| Hazard Information | Back Directory | [Uses]
N-Methyl-4-(2-methylphenyl)-6-(4-methyl-1-piperazinyl)-3-pyridinamine is used as a reactant in the synthesis of NK1 receptor antagonists via 1,4-Grignard addition/oxidation sequence to 6-chloronicotinic acid and derivatives. |
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