| Identification | Back Directory | [Name]
5-AMINO-3-CHLOROPYRIDAZINE | [CAS]
29049-45-4 | [Synonyms]
SW-103
SWF-103
6-Chloro-4-pyridazinamine
6-Chloropyridazin-4-amine
5-AMINO-3-CHLOROPYRIDAZINE
4-PyridazinaMine, 6-chloro-
3-Chloro-pyridazin-5-ylaMine
5-Amino-3-chloropyridazine 93%
5-AMINO-3-CHLOROPYRIDAZINE ISO 9001：2015 REACH | [Molecular Formula]
C4H4ClN3 | [MDL Number]
MFCD03085861 | [MOL File]
29049-45-4.mol | [Molecular Weight]
129.55 |
| Chemical Properties | Back Directory | [Melting point ]
153-154 ºC | [Boiling point ]
368.3±22.0 °C(Predicted) | [density ]
1.437 | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
solid | [pka]
4.55±0.10(Predicted) | [color ]
Light yellow to light brown |
| Hazard Information | Back Directory | [Uses]
6-Chloro-4-pyridazinamine (cas# 29049-45-4) is a compound useful in organic synthesis. | [Application]
5-Amino-3-chloropyrazine, as an important structural unit of heterocyclic structures, possesses diverse chemical reactivity due to its pyrazine ring skeleton, chlorine atom, and amino functional group, making it a key intermediate for the synthesis of bioactive drug molecules and agrochemicals. | [Synthesis]
General procedure for the synthesis of 6-chloro-4-amino pyridazine from 3,5-dichloropyridazine: 3,5-dichloropyridazine (1 g, 6.71 mmol, 1.0 eq.), ammonia (8 mL), and dioxane (2 mL) were added to a 25 mL round-bottom flask. The reaction mixture was stirred at 100 °C overnight. Upon completion of the reaction, the resulting solid was collected by filtration. A final 570 mg (62% yield) of 6-chloro-4-aminopyridazine was obtained as a brown solid. The product was analyzed by LC-MS to confirm: (ES, m/z): retention time (RT) = 0.434 min, LCMS purity 53%, m/z = 130 [M + 1]. | [References]
[1] Patent: WO2017/181177, 2017, A1. Location in patent: Paragraph 0941-0944 |
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| Company Name: |
Chem-Stone Co.,Ltd.
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| Telephone: |
020-82185713,82185709 13418171485 |
| Website: |
www.chem-stone.com |
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