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2911548-33-7

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2911548-33-7 Structure

2911548-33-7 Structure
IdentificationBack Directory
[Name]

SVC-02
[CAS]

2911548-33-7
[Synonyms]

SVC-02
Hazard InformationBack Directory
[Uses]

SVC-02 is a vasohibin (VASH) inhibitor with an IC50 value of 11 nM. SVC-02 reduces tubulin detyrosination. SVC-02 has the potential for the research of reduce myo-cardial stiffness and improve relaxation in Heart failure with preserved ejection fraction (HFpEF)[1].
[References]

[1] Eaton DM, et al. Vasohibin inhibition improves myocardial relaxation in a rat model of heart failure with preserved ejection fraction. Sci Transl Med. 2024 Jul 17;16(756):eadm8842. DOI:10.1126/scitranslmed.adm8842
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