| Chemical Properties | Back Directory | [Boiling point ]
562.7±50.0 °C(Predicted) | [density ]
1.19±0.1 g/cm3(Predicted) | [solubility ]
DMF: 30 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 0.25 mg/ml | [pka]
13.02±0.20(Predicted) |
| Hazard Information | Back Directory | [Description]
The actions of many clinical prostaglandins, including those used for estrous synchronization and for reduction of intraocular pressure, are mediated through the FP receptor. CAY10510 is an analog of PGF2α containing an acetylenic fluorobenzene substituent in the lower side chain. CAY10510 has an IC50 of 0.5 μM when tested for binding to the recombinant human FP receptor. | [Uses]
PGF2α analogue-1 is an analog of Dinoprost (HY-12956) containing an acetylenic fluorobenzene substituent in the lower side chain. |
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