| Chemical Properties | Back Directory | [density ]
1.356±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [pka]
1.821±0.10(predicted) | [Sequence]
Ac-Ala-Ser-{Aib}-Leu-Arg-Lys-Leu-{Aib}-{Lys(NOTA)}-Arg-Leu-Leu-NH2 |
| Hazard Information | Back Directory | [Uses]
NOTA-COG1410 forms triggering receptor expressed on myeloid cells 2 (TREM2) targeting radioligand for discovery and diagnosis of digestive system tumors through positron emission tomography/computed tomography[1]. NOTA-COG1410 can be used for the synthesis/research of Radionuclide-Drug Conjugates (RDCs). | [IC 50]
RDC Peptide | [References]
[1] Shi D, et al., Synthesis and Evaluation of?68Ga-NOTA-COG1410 Targeting to TREM2 of TAMs as a Specific PET Probe for Digestive Tumor Diagnosis. Anal Chem. 2022 Mar 8;94(9):3819-3830. DOI:10.1021/acs.analchem.1c04701 |
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| Company Name: |
YantaiBio
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| Tel: |
13758194781 15083780366 |
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