| Chemical Properties | Back Directory | [Boiling point ]
412.069±45.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.411±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
11.037±0.70(predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
Cisd2 agonist 1 (Compound 4q) is a Cisd2 agonist (EC50: 34 nM). Cisd2 agonist 1 enhances the Cisd2 expression and improves the pathological changes in the fatty livers. Cisd2 agonist 1 has good metabolic stability. Cisd2 agonist 1 can be used for research of NAFLD[1]. | [References]
[1] Yao CH, et al. Discovery of tetrasubstituted thiophenes as Cisd2 activators: A potential novel therapeutic option in nonalcoholic fatty liver disease. Eur J Med Chem. 2023 Oct 5;258:115583. DOI:10.1016/j.ejmech.2023.115583 |
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Biorbyt Ltd.
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+44 (0)1223 859 353 |
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http://www.biorbyt.com |
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