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2916433-81-1

2916433-81-1 Structure

2916433-81-1 Structure
IdentificationBack Directory
[Name]

PROTAC GPX4 degrader-1
[CAS]

2916433-81-1
[Synonyms]

PROTAC GPX4 degrader-1
[Molecular Formula]

C50H57ClN10O10
[MOL File]

2916433-81-1.mol
[Molecular Weight]

993.5
Chemical PropertiesBack Directory
[density ]

1.391±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

10.75±0.40(predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

PROTAC GPX4 degrader-1 (DC-2) is a PROTAC-based GPX4 degrader, with a DC50 of 0.03 μM in HT1080 cells[1].
[References]

[1] Han Wang, et al. Discovery of ML210-Based glutathione peroxidase 4 (GPX4) degrader inducing ferroptosis of human cancer cells. Eur J Med Chem. 2023 Jun 5;254:115343. DOI:10.1016/j.ejmech.2023.115343
2916433-81-1 suppliers list
Company Name: Bide Pharmatech Ltd.  
Tel: 400-1647117 13681763483
Website: https://www.bidepharm.com/
Company Name: Anhui JYHX CO., LTD.  
Tel: 0551-68788198 13295518198
Website: http://www.ahjyhx.cn
Company Name: Anhui Xtpeptide Biotechnology CO., LTD.  
Tel: 0551-68788198
Website: http://www.qingbio.com/
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