| Identification | Back Directory | [Name]
Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester | [CAS]
2921586-65-2 | [Synonyms]
Thieno[2,3-c]pyridine-3-carboxylic acid, 4,5,6,7-tetrahydro-2-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]amino]-, (9Z,12Z)-9,12-octadecadien-1-yl ester | [Molecular Formula]
C44H72N2O3S | [MOL File]
2921586-65-2.mol | [Molecular Weight]
709.12 |
| Chemical Properties | Back Directory | [Boiling point ]
800.5±65.0 °C(predicted) | [density ]
0.996±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [solubility ]
Ethanol: Soluble: = 10 mg/ml | [pka]
14.10±0.20(predicted) |
| Hazard Information | Back Directory | [Description]
Lipid 20b is a thiophene ionizable cationic lipid that has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.1 LNPs containing lipid 20b and encapsulating mRNA encoding a luciferase reporter induce bioluminescence in the lungs, spleen, and retina of mice.WARNING This product is not for human or veterinary use. | [References]
[1] YULIA EYGERIS. Thiophene-based lipids for mRNA delivery to pulmonary and retinal tissues.[J]. Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 11: e2307813120. DOI: 10.1073/pnas.2307813120 |
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