| Chemical Properties | Back Directory | [Boiling point ]
736.280±60.00 °C(Press: 760.00 Torr)(predicted) | [density ]
1.524±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
13.029±0.40(predicted) | [color ]
Yellow to orange |
| Hazard Information | Back Directory | [Uses]
Iscartrelvir (WU-04) is a non-covalent inhibitor of SARS-CoV-2, targeting the 3CLpro protein. Iscartrelvir has high inhibitory effect on the 3CLpro protein of 6 SARS-CoV-2 variants (Alpha, Beta, Gamma, Delta, Lambda and Omicron) and 2 coronaviruses (SARS-CoV and MERS-CoV)[1]. | [References]
[1] Wu J, et al. The molecular mechanism of non-covalent inhibitor WU-04 targeting SARS-CoV-2 3CLpro and computational evaluation of its effectiveness against mainstream coronaviruses. Phys Chem Chem Phys. 2023 Sep 13;25(35):23555-23567.. . DOI:10.1039/d3cp03828a |
|
|