CBC-1 (50 mg/kg; i.p.; once daily for 16 days) can effectively inhibit tumor growth in xenograft models, with a remarkable tumor inhibition rate of 68% in BALB/c/nu/nu nude mice[1].
| Animal Model: | Tumour xenograft BALB/c/nu/nu nude mice model[1]. |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal injection (i.p.); Once daily for 16 days |
| Result: | Significantly reduced the size and weight of HT29 tumor xenografts.
Decreased the protein expression of GLI -1.
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