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2924824-04-2

2924824-04-2 Structure

2924824-04-2 Structure
IdentificationBack Directory
[Name]

Desthiobiotin-Iodoacetamide
[CAS]

2924824-04-2
[Synonyms]

Desthiobiotin-Iodoacetamide
[Molecular Formula]

C14H25IN4O3
[MOL File]

2924824-04-2.mol
[Molecular Weight]

424.28
Chemical PropertiesBack Directory
[Boiling point ]

710.7±45.0 °C(predicted)
[density ]

1.425±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

13.68±0.46(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Desthiobiotin-Iodoacetamide can be used as an ADC Linker. Desthiobiotin-Iodoacetamide also acts as a probe used to label the the Oridonin (HY-N0004)-treated cell lysis[1].
[References]

[1] Zhang Y, et al. Oridonin acts as a novel senolytic by targeting glutathione S-transferases to activate the ROS-p38 signaling axis in senescent cells. Chem Commun (Camb). 2022 Nov 29;58(95):13250-13253. DOI:10.1039/d2cc05278d
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