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2925457-27-6

2925457-27-6 Structure

2925457-27-6 Structure
IdentificationBack Directory
[Name]

BChE/HDAC6-IN-1
[CAS]

2925457-27-6
[Synonyms]

BChE/HDAC6-IN-1
Hazard InformationBack Directory
[Uses]

BChE/HDAC6-IN-1 is a potent and selective dual BChE/HDAC6 inhibitor with IC50 values of 4 and 8.9 nM, respectively. BChE/HDAC6-IN-1 ameliorates the cognitive impairment in an Aβ1–42-induced mouse model and has the potental for AD research[1].
[References]

[1] Lei Wang, ET AL. Design, Synthesis, and Proof of Concept of Balanced Dual Inhibitors of Butyrylcholinesterase (BChE) and Histone Deacetylase 6 (HDAC6) for the Treatment of Alzheimer's Disease. ACS Chem Neurosci. 2023 Sep 6;14(17):3226-3248. DOI:10.1021/acschemneuro.3c00358
2925457-27-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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