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2930378-91-7

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2930378-91-7 Structure

2930378-91-7 Structure
IdentificationBack Directory
[Name]

GAK inhibitor 49 hydrochloride
[CAS]

2930378-91-7
[Synonyms]

[Molecular Formula]

C20H22N2O5.ClH
[MOL File]

2930378-91-7.mol
[Molecular Weight]

406.86
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to yellow
Hazard InformationBack Directory
[Uses]

GAK inhibitor 49 hydrochloride is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a Ki of 0.54 nM and a cell IC50 of 56 nM. GAK inhibitor 49 hydrochloride also shows binding to RIPK2[1].
[References]

[1] Asquith CRM, et al. Identification and Optimization of 4-Anilinoquinolines as Inhibitors of Cyclin G Associated Kinase. ChemMedChem. 2018;13(1):48-66. DOI:10.1002/cmdc.201700663
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