| Hazard Information | Back Directory | [Uses]
Antileishmanial agent-16 (compound 14c) is an anti-Leishmania agent. Antileishmanial agent-16 has superior anti-Leishmania major promastigotes activity (IC50 = 0.59 μM) and anti-Leishmania major amastigotes activity (IC50 = 0.81 μM). Antileishmanial agent-16 has good safety to mammalian cells (VERO cells)[1]. | [References]
[1] Hassan NW, et al. Modulating leishmanial pteridine metabolism machinery via some new coumarin-1,2,3-triazoles: Design, synthesis and computational studies. Eur J Med Chem. 2023 May 5;253:115333. DOI:10.1016/j.ejmech.2023.115333 |
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