| Chemical Properties | Back Directory | [density ]
1.412±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | [form ]
Solid | [pka]
14.059±0.40(predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
PROTAC K-Ras Degrader-4 (compound I-27) is a PROTAC that can effectively degrade K-Ras. PROTAC K-Ras Degrader-4 can be used in cancer research[1]. | [IC 50]
K-RAS | [References]
[1] Popow J, et al. Targeting cancer with small-molecule pan-KRAS degraders. Science. 2024 Sep 20;385(6715):1338-1347. DOI:10.1126/science.adm8684 |
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