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UniPR505 (Compound 14) is an EphA2 antagonist with an IC50 of 0.95 μM. UniPR505 displays anti-angiogenic properties[1]. | [References]
[1] Incerti M, et al. Optimization of EphA2 antagonists based on a lithocholic acid core led to the identification of UniPR505, a new 3α-carbamoyloxy derivative with antiangiogenetic properties. Eur J Med Chem. 2020 Mar 1;189:112083. DOI:10.1016/j.ejmech.2020.112083 |
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