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2946-01-2

2946-01-2 Structure

2946-01-2 Structure
IdentificationBack Directory
[Name]

1-[7,7-dimethyl-4-(4-methylphenyl)sulfonyloxy-2,6,8-trioxabicyclo[3.3.0]oct-3-yl]ethane-1,2-diol
[CAS]

2946-01-2
[Synonyms]

1,2-O-Isopropylidene-α-D-glucofuranose 3-tosylate
1-[7,7-dimethyl-4-(4-methylphenyl)sulfonyloxy-2,6,8-trioxabicyclo[3.3.0]oct-3-yl]ethane-1,2-diol
[Molecular Formula]

C16H22O8S
[MOL File]

2946-01-2.mol
[Molecular Weight]

374.41
Chemical PropertiesBack Directory
[Boiling point ]

557.549±50.00 °C(Press: 760.00 Torr)(predicted)
[density ]

1.449±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
[solubility ]

Chloroform; Methanol
[form ]

Solid
[pka]

13.507±0.20(predicted)
[color ]

Yellow
Hazard InformationBack Directory
[Uses]

1,2-O-Isopropylidene-α-D-glucofuranose 3-tosylate is an intermediate in synthesizing 6R,7R,8aR-Glucosepane (G595300), one of the eight diastereomers of glucosepane. Glucosepane is a structurally complex protein posttranslational modification that is believed to exist in all living organisms. Research in humans suggests that glucosepane plays a critical role in the pathophysiology of both diabetes and human aging.
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