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296250-54-9

296250-54-9 Structure

296250-54-9 Structure
IdentificationBack Directory
[Name]

BMS-341400 methanesulfonate >=98% (HPLC)
[CAS]

296250-54-9
[Synonyms]

BMS-341400 methanesulfonate >=98% (HPLC)
[Molecular Formula]

C24H26ClN9O5S
[MOL File]

296250-54-9.mol
[Molecular Weight]

588.04
Hazard InformationBack Directory
[Uses]

BMS-341400 mesylate (Compound 6) is an orally active and a selective phosphodiesterase 5 (PDE5) inhibitor, with IC50 of 0.3 nM. BMS-341400 mesylate can be used for research of erectile dysfunction[1].
[IC 50]

PDE5: 0.3 nM (IC50)
[References]

[1] Yu G, et al. Substituted pyrazolopyridopyridazines as orally bioavailable potent and selective PDE5 inhibitors: potential agents for treatment of erectile dysfunction. J Med Chem. 2003 Feb 13;46(4):457-60. DOI:10.1021/jm0256068
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