| Identification | Back Directory | [Name]
Ethanone, 1-[7-[(3,5-dimethoxyphenyl)amino]-5-(1-methyl-1H-pyrazol-5-yl)-2-benzofuranyl]- | [CAS]
2987726-27-0 | [Synonyms]
Ethanone, 1-[7-[(3,5-dimethoxyphenyl)amino]-5-(1-methyl-1H-pyrazol-5-yl)-2-benzofuranyl]- | [Molecular Formula]
C22H21N3O4 | [MOL File]
2987726-27-0.mol | [Molecular Weight]
391.42 |
| Hazard Information | Back Directory | [Uses]
STAT3-IN-9 is a potent STAT3 inhibitor. STAT3-IN-9 inhibits the activation of STAT3 (Tyr705) without influencing the phosphorylation of STAT1 (Tyr701). STAT3-IN-9 induces apoptosis and cell cycle arrest at the G2/M phase[1]. | [IC 50]
STAT3 | [References]
[1] Wang F, et al. Identification of novel STAT3 inhibitors bearing 2-acetyl-7-phenylamino benzofuran scaffold for antitumour study. Bioorg Med Chem. 2020; 28(24):115822. DOI:10.1016/j.bmc.2020.115822 |
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