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2987726-27-0

2987726-27-0 Structure

2987726-27-0 Structure
IdentificationBack Directory
[Name]

Ethanone, 1-[7-[(3,5-dimethoxyphenyl)amino]-5-(1-methyl-1H-pyrazol-5-yl)-2-benzofuranyl]-
[CAS]

2987726-27-0
[Synonyms]

Ethanone, 1-[7-[(3,5-dimethoxyphenyl)amino]-5-(1-methyl-1H-pyrazol-5-yl)-2-benzofuranyl]-
[Molecular Formula]

C22H21N3O4
[MOL File]

2987726-27-0.mol
[Molecular Weight]

391.42
Chemical PropertiesBack Directory
[Boiling point ]

589.3±50.0 °C(predicted)
[density ]

1.27±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

2.29±0.50(predicted)
Hazard InformationBack Directory
[Uses]

STAT3-IN-9 is a potent STAT3 inhibitor. STAT3-IN-9 inhibits the activation of STAT3 (Tyr705) without influencing the phosphorylation of STAT1 (Tyr701). STAT3-IN-9 induces apoptosis and cell cycle arrest at the G2/M phase[1].
[IC 50]

STAT3
[References]

[1] Wang F, et al. Identification of novel STAT3 inhibitors bearing 2-acetyl-7-phenylamino benzofuran scaffold for antitumour study. Bioorg Med Chem. 2020; 28(24):115822. DOI:10.1016/j.bmc.2020.115822
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