| Identification | Back Directory | [Name]
UCYGAGOHASJWLC-ACHOKTOGSA-L | [CAS]
299216-98-1 | [Synonyms]
08:0 PI(3)P
UCYGAGOHASJWLC-ACHOKTOGSA-L
1-(1,2-dioctanoylphosphatidyl)inositol-3-phosphate, disodium salt | [Molecular Formula]
C25H49NaO16P2 | [MDL Number]
MFCD32689409 | [MOL File]
299216-98-1.mol | [Molecular Weight]
690.59 |
| Chemical Properties | Back Directory | [storage temp. ]
-20°C | [solubility ]
Water: 50 mg/ml | [form ]
A lyophilized powder | [InChIKey]
IHRPLAYZBAFIEF-ACHOKTOGSA-N | [SMILES]
[H][C@@](COP([O-])(O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OP([O-])(O)=O)[C@H]1O)=O)(OC(CCCCCCC)=O)COC(CCCCCCC)=O.[NH4+].[NH4+] |
| Hazard Information | Back Directory | [Description]
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3)-P1 (1,2-dioctanoyl) is a synthetic analog of natural PtdIns featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and DAG stereochemistry as the natural compound. PtdIns-(3)-P1 can be phosphorylated to di- (PtdIns-P2; PIP2) and triphosphates (PtdIns-P3; PIP3) by phosphatidyl inositol (PI)-specific kinases. | [Uses]
08:0 PI(3)P has been used in the preparation of model membrane for protein reconstitution and structural studies. | [Uses]
Glycerophospholipids act as regulators of various enzyme activities, and can be used as biological markers to indicate pathological states. | [General Description]
Phosphatidylinositol 3-monophosphate (PI3P) is a lipid, found abundantly in eukaryotic cells. It is also present at low level in mammalian cells. | [Biochem/physiol Actions]
Phosphatidylinositol 3-monophosphate (PI3P) participates in vesicular trafficking processes. It also plays a key role in endocytosis. |
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Sigma-Aldrich
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Merck KGaA
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Creative Enzymes
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