ChemicalBook--->CAS DataBase List--->3000549-26-5

3000549-26-5

3000549-26-5 Structure

3000549-26-5 Structure
IdentificationBack Directory
[Name]

OICR-8268
[CAS]

3000549-26-5
[Synonyms]

OICR-8268
Hazard InformationBack Directory
[Uses]

OICR-8268 is a reversible DCAF1 ligand that binds to the DCAF1 WDR domain with a Kd of 38 nM. OICR-8268 can enable the development of DCAF1-based PROTACs[1].
[IC 50]

Cereblon
[References]

[1] Alice Shi Ming Li, et al. Discovery of Nanomolar DCAF1 Small Molecule Ligands. J Med Chem. 2023 Apr 13;66(7):5041-5060. DOI:10.1021/acs.jmedchem.2c02132
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