| Identification | Back Directory | [Name]
L-Leucinamide, glycyl-L-leucyl-L-phenylalanyl-L-α-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valylglycyl-L-alanyl-L-isoleucylglycyl-L-seryl- | [CAS]
302343-06-2 | [Synonyms]
L-Leucinamide, glycyl-L-leucyl-L-phenylalanyl-L-α-aspartyl-L-isoleucyl-L-valyl-L-lysyl-L-lysyl-L-valyl-L-valylglycyl-L-alanyl-L-isoleucylglycyl-L-seryl- | [Molecular Formula]
C76H131N19O19 | [MOL File]
302343-06-2.mol | [Molecular Weight]
1614.97 |
| Chemical Properties | Back Directory | [Boiling point ]
1816.8±65.0 °C(Predicted) | [density ]
1.200±0.06 g/cm3(Predicted) | [pka]
4.20±0.10(Predicted) | [Sequence]
Gly-Leu-Phe-Asp-Ile-Val-Lys-Lys-Val-Val-Gly-Ala-Ile-Gly-Ser-Leu-NH2 |
| Hazard Information | Back Directory | [Uses]
Aurein 2.3 is an antibiotic antimicrobial peptide. Aurein 2.3 partially inhibits E.coli ATPase activity and inhibits cell growth[1][2]. | [References]
[1] Rozek T, et al. The antibiotic and anticancer active aurein peptides from the Australian Bell Frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2. Eur J Biochem. 2000 Sep;267(17):5330-41. DOI:10.1046/j.1432-1327.2000.01536.x
[2] Laughlin TF, et al. Inhibition of Escherichia coli ATP synthase by amphibian antimicrobial peptides. Int J Biol Macromol. 2010 Apr 1;46(3):367-74. DOI:10.1016/j.ijbiomac.2010.01.015 |
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