| Identification | Back Directory | [Name]
ethyl 2-(2-(2-imino-4-oxothiazolidin-5-yl)acetamido)-4,5-dimethylthiophene-3-carboxylate | [CAS]
302804-57-5 | [Synonyms]
ethyl 2-(2-(2-imino-4-oxothiazolidin-5-yl)acetamido)-4,5-dimethylthiophene-3-carboxylate
ethyl 2-{[(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetyl]amino}-4,5-dimethylthiophene-3-carboxylate
3-Thiophenecarboxylic acid, 2-[[2-(2-amino-4,5-dihydro-4-oxo-5-thiazolyl)acetyl]amino]-4,5-dimethyl-, ethyl ester | [Molecular Formula]
C14H17N3O4S2 | [MDL Number]
MFCD01848166 | [MOL File]
302804-57-5.mol | [Molecular Weight]
355.43 |
| Chemical Properties | Back Directory | [density ]
1.53±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [solubility ]
DMSO: 100mg/mL | [form ]
solid | [pka]
13.04±0.70(Predicted) | [color ]
off-white |
| Hazard Information | Back Directory | [Uses]
A cell-permeable iminooxothiazolidine compound that is shown to counteract the antagonizing effect of SARP-2/sFRP-1 (secreted frizzled related protein-1) against Wnt-3/frizzled interaction and restore cellular response to Wnt-3 stimulation (by a 2.3-fold enhancement at 15 µM) in U2OS-based reporter assays. Also reported to increase total bone area and the number of osteoblasts (by ~20% and ~45%, respectively) in a murine ex vivo calvarial bone formation assay. |
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| Company Name: |
Merck KGaA
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| Telephone: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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