| Hazard Information | Back Directory | [Uses]
LCC-12 formic is a dimer of metformin that targets mitochondrial copper(II), leading to a decrease in the NAD(H) pool and modulation of inflammatory responses. LCC-12 formic reduces inflammation in mouse models of bacterial and viral infections. LCC-12 formic also serves as a tool for investigating metabolic diseases through its effects on cell plasticity and epigenetic programming. | [References]
[1] A druggable copper-signalling pathway that drives inflammation DOI:10.1038/s41586-023-06017-4 |
|
|