| Identification | Back Directory | [Name]
KIF18A-IN-13 | [CAS]
3029503-57-6 | [Synonyms]
KIF18A-IN-13
Benzamide, N-[6-(4,4-difluoro-1-piperidinyl)-4-methyl-2-pyridinyl]-4-[[(2-hydroxyethyl)sulfonyl]amino]-2-spiro[2.5]oct-5-en-6-yl- | [Molecular Formula]
C28H34F2N4O4S | [MOL File]
3029503-57-6.mol | [Molecular Weight]
560.66 |
| Hazard Information | Back Directory | [Uses]
KIF18A-IN-13 (Compound 16) is an effective and orally active inhibitor of KIF18A with anticancer activity in vivo. KIF18A-IN-13 can be utilized for research in ovarian cancer[1]. | [References]
[1] Zhang C, et al. Design, Biological Characterization, and Discovery of Novel Cyclohexenyl Derivatives as Kinesin KIF18A Inhibitors for the Treatment of Ovarian Cancer[J]. ACS Medicinal Chemistry Letters, 2024. |
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