| Identification | Back Directory | [Name]
SALOR-INT L135356-1EA | [CAS]
302953-06-6 | [Synonyms]
DCHC
SALOR-INT L135356-1EA
DCHC >=98% (HPLC), solid
3-(2,4-Dichlorophenyl)-7-hydroxy-4H-chromen-4-one | [Molecular Formula]
C15H8Cl2O3 | [MDL Number]
MFCD01848896 | [MOL File]
302953-06-6.mol | [Molecular Weight]
307.13 |
| Chemical Properties | Back Directory | [Boiling point ]
498.5±45.0 °C(Predicted) | [density ]
1.523±0.06 g/cm3(Predicted) | [solubility ]
DMSO: >20mg/mL | [form ]
solid | [pka]
6.72±0.20(Predicted) | [color ]
yellow |
| Hazard Information | Back Directory | [Uses]
DCHC is a SIRT1 activator but does not induce SIRT1 expression. DCHC can be used for mitochondrial damage related studies[1]. | [Definition]
ChEBI: 3-(2,4-dichlorophenyl)-7-hydroxy-4H-chromen-4-one is a member of the class of 7-hydroxyisoflavones that is 3-phenyl-4H-chromen-4-one which is substituted by a hydroxy group at position 7 and chloro groups at positions 2' and 4'. It is a SIRT1 activator. It is a member of 7-hydroxyisoflavones and a dichlorobenzene. | [IC 50]
SIRT1 | [References]
[1] Rasbach KA, et al. Isoflavones promote mitochondrial biogenesis. J Pharmacol Exp Ther. 2008 May;325(2):536-43. DOI:10.1124/jpet.107.134882 |
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| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
OTAVA chemicals
|
| Tel: |
416 305 9979 (Canada) |
| Website: |
www.otavachemicals.com |
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