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3030577-05-7

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3030577-05-7 Structure

3030577-05-7 Structure
IdentificationBack Directory
[Name]

NA
[CAS]

3030577-05-7
[Synonyms]

[Molecular Formula]

C32H38ClF2N5O3
[MOL File]

3030577-05-7.mol
[Molecular Weight]

614.13
Chemical PropertiesBack Directory
[Boiling point ]

791.1±70.0 °C(predicted)
[density ]

1.43±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
Hazard InformationBack Directory
[Uses]

KRAS inhibitor-25 (compound 151a) is a pyridopyrimidine KRAS inhibitor, with an IC50 of < 100 nM against KRas G12V, KRas WT and KRas G12R[1].
[IC 50]

KRas G12C: < 100 nM (IC50); K-Ras WT: < 100 nM (IC50); KRas G12R: < 100 nM (IC50)
[References]

[1] James Paul LAJINESS, et al. Pyridopyrimidine kras inhibitors. Patent WO 2024/040131 A1.
3030577-05-7 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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