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3032760-71-4

3032760-71-4 Structure

3032760-71-4 Structure
IdentificationBack Directory
[Name]

EGFR T790M/L858R-IN-6
[CAS]

3032760-71-4
[Synonyms]

EGFR T790M/L858R-IN-6
[Molecular Formula]

C27H27N7O2
[MOL File]

3032760-71-4.mol
[Molecular Weight]

481.55
Chemical PropertiesBack Directory
[Boiling point ]

757.7±70.0 °C(predicted)
[density ]

1.31±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

14.64±0.10(predicted)
Hazard InformationBack Directory
[Uses]

EGFR T790M/L858R-IN-6 (compound 53), a pyrimidine compound, is a potent EGFR T790M/L858R inhibitor. EGFR T790M/L858R-IN-6 shows 90.88% enzyme activity inhibition with 0.05 μM[1].
[IC 50]

EGFR (L858R/T790M)
[References]

[1] Guoqing Paul Chen, et al. Novel pyrimidine compound as kinase inhibitors with biological activities on egfr mutants. WO2024064091A1.
3032760-71-4 suppliers list
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