ChemicalBook--->CAS DataBase List--->3032970-74-1

3032970-74-1

3032970-74-1 Structure

3032970-74-1 Structure
IdentificationBack Directory
[Name]

PB94
[CAS]

3032970-74-1
[Synonyms]

PB94
[Molecular Formula]

C29H33N3O4
[MOL File]

3032970-74-1.mol
[Molecular Weight]

487.59
Chemical PropertiesBack Directory
[density ]

1.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[form ]

Solid
[pka]

8.62±0.47(predicted)
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

PB94 is a selective HDAC11 inhibitor (IC50=108 nM). PB94 can be radiolabeled as [11C]-PB94 for use in positron emission tomography (PET), as well as brain uptake and metabolic properties in administered live animals. PB94 improves neuropathic pain in mice and could be used to study neurological indications[1].
[References]

[1] Bai P et al. Development and Pharmacochemical Characterization Discover a Novel Brain-Permeable HDAC11-Selective Inhibitor with Therapeutic Potential by Regulating Neuroinflammation in Mice. J Med Chem. 2023 Nov 16. DOI:10.1021/acs.jmedchem.3c01491
3032970-74-1 suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 021-13816613772 13816613772
Website: https://www.chemicalbook.com/ShowSupplierProductsList16976/0.htm
Company Name: Soochow Chirally Material Science and Technology Co.,Ltd  
Tel: 0512-66834346 17751187418
Website: http://www.krl-tech.com/
Company Name: Shandong Dongde New Materials Co., Ltd  
Tel: 15666167041
Website:
Tags:3032970-74-1 Related Product Information

  • HomePage | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Privacy | Terms | About Us
  • All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
    According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.
  • Copyright © 2023 ChemicalBook All rights reserved.