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3033950-86-3

3033950-86-3 Structure

3033950-86-3 Structure
IdentificationBack Directory
[Name]

CDK4/6-IN-19
[CAS]

3033950-86-3
[Synonyms]

CDK4/6-IN-19
[Molecular Formula]

C23H27ClFN5O3S
[MOL File]

3033950-86-3.mol
[Molecular Weight]

508.01
Chemical PropertiesBack Directory
[Boiling point ]

722.9±70.0 °C(predicted)
[density ]

1.57±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

13.81±0.40(predicted)
Hazard InformationBack Directory
[Uses]

CDK4/6-IN-19 (Compound II-7) is a CDK4/CDK6 inhibitor with IC50 values ??of 0.2, 5.0 nM, respectively. CDK4/6-IN-19 also inhibits cell proliferation and can be used in cancer research[1].
[IC 50]

CDK4: 0.2 nM (IC50); CDK6: 5.0 nM (IC50)
[References]

[1] HU, Pu, et al. 2-aminopyrimidine compound, and use and pharmaceutical composition thereof.WO2024066986A1.
3033950-86-3 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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