| Identification | Back Directory | [Name]
CDK2/4-IN-2 | [CAS]
3034898-59-1 | [Synonyms]
CDK2/4-IN-2
5-Thiazolemethanol, α-methyl-2-[2-[[1-(1H-pyrazol-4-ylsulfonyl)-4-piperidinyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]- | [Molecular Formula]
C18H20F3N7O3S2 | [MOL File]
3034898-59-1.mol | [Molecular Weight]
503.52 |
| Chemical Properties | Back Directory | [Boiling point ]
760.8±70.0 °C(predicted) | [density ]
1.572±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
11.13±0.50(predicted) |
| Hazard Information | Back Directory | [Uses]
CDK2/4-IN-2 (compound 56) is a CDK2 and CDK4 dual inhibitor with IC50s less than 100 nM. CDK2/4-IN-2 can be used in the study of cancer[1]. | [References]
[1] Xiaowei Wu, et al. Cdk inhibitors and their use as pharmaceuticals. US, WO2024077216A1. 2024-04-11. |
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