| Identification | Back Directory | [Name]
6-Bromo-2-chloro-3-(2,6-dioxopiperidin-3-yl)benzonitrile | [CAS]
3036607-67-4 | [Synonyms]
CRBN ligand-111
6-Bromo-2-chloro-3-(2,6-dioxopiperidin-3-yl)benzonitrile |
| Hazard Information | Back Directory | [Uses]
CRBN ligand-111 is a CRBN-type E3 ubiquitin ligase ligand that can be used to prepare PROTAC. | [IC 50]
Cereblon | [References]
[1] Mileti? N, et al. Workflow for E3 Ligase Ligand Validation for PROTAC Development. ACS Chem Biol. 2025 Feb 21;20(2):507-521. DOI:10.1021/acschembio.4c00812 |
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