| Identification | Back Directory | [Name]
KYNURAMINE DIHYDROBROMIDE | [CAS]
304-47-2 | [Synonyms]
KYNURAMINE DIHYDROBROMIDE
3-(2-aminophenyl)-3-oxopropanamine
Kynuramine dihydrobromide crystalline
3-[2-AMINOPHENYL]-3-OXOPROPANAMINE DIHYDROBROMIDE
3-aMino-1-(2-aMinophenyl)propan-1-one dihydrobroMide
3-Amino-1-(2-aminophenyl)-1-propanone Dihydrobromide | [Molecular Formula]
C9H14Br2N2O | [MDL Number]
MFCD00050683 | [MOL File]
304-47-2.mol | [Molecular Weight]
326.03 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C
| [solubility ]
DMSO (Slightly), Methanol (Slightly),??Water (Very Slightly) | [form ]
crystalline
| [color ]
light yellow
| [Water Solubility ]
water: 50mg/mL, clear to slightly hazy | [Stability:]
Hygroscopic | [InChI]
1S/C9H12N2O.BrH/c10-6-5-9(12)7-3-1-2-4-8(7)11;/h1-4H,5-6,10-11H2;1H | [InChIKey]
YUPVVZSYBUIDQR-UHFFFAOYSA-N | [SMILES]
Br.NCCC(=O)c1ccccc1N |
| Hazard Information | Back Directory | [Uses]
Kynuramine dihydrobromide has been used as a substrate for monoamine oxidase. | [Biochem/physiol Actions]
Kynuramine dihydrobromide is a substrate for the enzyme monoamine oxidase. The end product is the formation of fluorescence detectable 4-hydroxyquinoline (4-HOQ) measured in a fluorescence spectrophotometer at 380 nm. | [in vivo]
Kynuramine dihydrobromide (0.064-8 μg; ICV; single does) facilitates lordosis behavior in estrogen-primed ovariectomized rats[3].
Kynuramine dihydrobromide (1.25-5.0 mg/kg; i.v.; single does) increases heart rate and blood pressure in rats[4]. | Animal Model: | Female rats[3]. | | Dosage: | 0.064, 0.32, 1.6 or 8 μg. | | Administration: | Intraventricular injection; single does. | | Result: | Produced facilitation of lordosis behavior. |
| Animal Model: | Male rats (about 200g)[4]. | | Dosage: | 1.25, 2.5 and 5.0 mg/kg. | | Administration: | Intravenous injection; single does. | | Result: | Promoted heart rate and blood pressure. |
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Sigma-Aldrich
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Energy Chemical
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Merck KGaA
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