Identification | Back Directory | [Name]
PDE4-IN-19 | [CAS]
3042879-82-0 | [Synonyms]
PDE4-IN-19 Pyrido[2′,3′:4,5]pyrrolo[1,2-a]pyrazin-9(6H)-one, 10-(4-chloro-3-fluorophenyl)-7,8-dihydro-8-(2-hydroxyethyl)- | [Molecular Formula]
C18H15ClFN3O2 | [MOL File]
3042879-82-0.mol | [Molecular Weight]
359.78 |
Hazard Information | Back Directory | [Uses]
PDE4-IN-19 (compound 1) is a PDE4 inhibitor, with IC50 values of <10 nM and 10-100 nM for PDE4B1 and PDE4D3, respectively[1]. | [IC 50]
PDE4B1: <10 nM (IC50); PDE4D3: 10-100 nM (IC50) | [References]
[1] David Zhang, et al. Azaindole compounds and their use as phosphodiesterase inhibitors. Patent WO2024118524A1. |
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