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3043670-68-1

3043670-68-1 Structure

3043670-68-1 Structure
IdentificationBack Directory
[Name]

PROTAC K-Ras Degrader-3
[CAS]

3043670-68-1
[Synonyms]

PROTAC K-Ras Degrader-3
[Molecular Formula]

C57H67F2N9O6
[MOL File]

3043670-68-1.mol
[Molecular Weight]

1012.2
Chemical PropertiesBack Directory
[density ]

1.43±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka]

8.40±0.40(predicted)
Hazard InformationBack Directory
[Uses]

PROTAC K-Ras Degrader-3 (compound 40) is a PROTAC degrader of K-Ras with a DC50 of ≤ 1 nM against SW620 KRAS G12D, and a GI50 of ≤ 10 nM against SW620 3D cell growth. PROTAC K-Ras Degrader-3 can be utilized in cancer research[1].
[IC 50]

KRas G12D
[References]

[1] Robert L, et al. Glutarimide-containing pan-kras-mutant degrader compounds and uses thereof, WO2024118966A1, 2024-06-06
3043670-68-1 suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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